OR1L3

Across TCGA cell cohorts, OR1L3 RNA expression is significantly associated with the mutation status of many other genes, with 474 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR1L3-associated genes across cancer lineages are HUWE1, ATP7A, and MUC2. Each is linked with OR1L3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR1L3-to-partner and partner-to-OR1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HUWE1 grouped by OR1L3-low versus OR1L3-high in SKIN.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L3→partner) and Y-score (partner→OR1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HUWE1 →	+2.415	+0.008	.009	.001	3	4
SKIN	ATP7A →	+4.415	+0.022	.007	<.001	3	3
SKIN	MUC2 →	+2.678	+0.009	.005	<.001	3	3
SKIN	MPHOSPH9 →	+3.415	+0.013	.001	<.001	3	3
STOMACH	RB1 →	+3.209	+0.014	.007	<.001	3	3
CNS	HIP1R →	+3.700	+0.026	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 474 associations by consensus.

HUWE1 by OR1L3 expression — SKIN

Explore this box plot interactively →