OR1L3

Across TCGA cell cohorts, OR1L3 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR1L3-associated genes across cancer lineages are IDI2, ASB17, and CST9. Each is linked with OR1L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1L3-to-partner and partner-to-OR1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IDI2 grouped by OR1L3-low versus OR1L3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L3→partner) and Y-score (partner→OR1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IDI2 →	+0.029	+4.029	<.001	.009	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	CST9 →	+0.005	+4.807	<.001	.003	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

IDI2 by OR1L3 expression — OVARY

Explore this box plot interactively →