OR1J1

Across TCGA patient cohorts, OR1J1 mutation is significantly associated with the RNA expression of many other genes, with 1,202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1J1-associated genes across cancer lineages are LINC02319, MIR6776, and TAF9. Each is linked with OR1J1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1J1-to-partner and partner-to-OR1J1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02319 grouped by OR1J1-low versus OR1J1-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1J1→partner) and Y-score (partner→OR1J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LINC02319 →	+1.190	+4.459	<.001	.005	3	2
GBM	MIR6776 →	+0.865	+4.552	<.001	.004	3	2
UCEC	TAF9 →	+0.728	+3.480	<.001	.002	3	2
SKCM	RAD17 →	+0.541	+2.813	.008	.001	3	2
UCEC	SEC13 →	+0.409	+2.625	.005	.005	3	2
UCEC	KIAA1841 →	+0.625	+3.499	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,202 associations by consensus.

LINC02319 by OR1J1 expression — GBM

Explore this box plot interactively →