OR1F1

Across TCGA patient cohorts, OR1F1 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1F1-associated genes across cancer lineages are CLP, DC, and Hepatocytes. Each is linked with OR1F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1F1-to-partner and partner-to-OR1F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by OR1F1-low versus OR1F1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1F1→partner) and Y-score (partner→OR1F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CLP →	+0.054	+1.697	.023	.012	3	1
UCEC	DC →	+0.022	+2.326	.033	.036	3	1
UCEC	Hepatocytes →	+0.020	+3.747	<.001	.001	3	1
UCEC	Basophils →	+0.168	+3.000	.048	.036	3	1
UCEC	Pericytes →	+0.038	+3.113	.004	<.001	3	1
UCEC	Skeletal muscle →	+0.054	+2.332	.013	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CLP by OR1F1 expression — SKCM

Explore this box plot interactively →