Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, OR1E3 RNA expression is significantly associated with the mutation status of many other genes, with 54 significant associations in total. STOMACH shows the largest number of these associations.
The most reproducible OR1E3-associated genes across cancer lineages are DEPDC5, FAM149A, and TMPRSS15. Each is linked with OR1E3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1E3-to-partner and partner-to-OR1E3 results are reported.
Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEPDC5 grouped by OR1E3-low versus OR1E3-high in OESOPHAGUS.
RNA expression associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (OR1E3→partner) and Y-score (partner→OR1E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.