OR1E3

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR1E3 RNA expression is significantly associated with the mutation status of many other genes, with 54 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OR1E3-associated genes across cancer lineages are DEPDC5, FAM149A, and TMPRSS15. Each is linked with OR1E3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1E3-to-partner and partner-to-OR1E3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEPDC5 grouped by OR1E3-low versus OR1E3-high in OESOPHAGUS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1E3→partner) and Y-score (partner→OR1E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSDEPDC5 →+4.906+0.036.006<.00131
OESOPHAGUSFAM149A →+4.906+0.036.006<.00131
OESOPHAGUSTMPRSS15 →+4.906+0.036.006<.00131
OESOPHAGUSZBTB40 →+4.906+0.036.006<.00131
OESOPHAGUSCYFIP1 →+4.906+0.036.006<.00131
SKINMUCL3 →+4.022+0.018.006<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

DEPDC5 by OR1E3 expression — OESOPHAGUS

Box plot of DEPDC5 in OR1E3-low vs OR1E3-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration