OR1E2

Across TCGA patient cohorts, OR1E2 protein abundance is significantly associated with the RNA expression of many other genes, with 255 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1E2-associated genes across cancer lineages are TMED8, POLR1F, and PRKAG2. Each is linked with OR1E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1E2-to-partner and partner-to-OR1E2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OR1E2 versus TMED8 in UCEC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1E2→partner) and Y-score (partner→OR1E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMED8 →	-0.504	-0.717	.001	.001	3	1
UCEC	POLR1F →	-0.599	-0.664	.007	.005	3	1
UCEC	PRKAG2 →	-1.048	-0.451	.003	.003	3	1
UCEC	TDP2 →	-0.455	-0.476	<.001	.006	3	1
UCEC	CILK1 →	-0.736	-0.592	.004	.006	3	1
UCEC	TRIM38 →	-0.635	-0.571	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 255 associations by consensus.

OR1E2 vs TMED8 — UCEC

Explore this scatter interactively →