OR1E2

Across TCGA pan-cancer cohorts, OR1E2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR1E2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR1E2 RNA is repressed in tumor relative to normal tissue. In most cancer types OR1E2 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

BRCA and KIRP are the cancer types where OR1E2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR1E2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.017	.001	6	view →
KIRP	All	All	−0.009	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

OR1E2–BRCA

Open the BRCA breakdown →