OR1E1

Across TCGA cell cohorts, OR1E1 RNA expression is significantly associated with the mutation status of many other genes, with 84 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR1E1-associated genes across cancer lineages are ADGRB3, ARID3A, and ITPR2. Each is linked with OR1E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1E1-to-partner and partner-to-OR1E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADGRB3 grouped by OR1E1-low versus OR1E1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1E1→partner) and Y-score (partner→OR1E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ADGRB3 →	+4.870	+0.027	.001	<.001	3	2
PANCREAS	ARID3A →	+4.029	+0.004	.007	<.001	3	1
PANCREAS	ITPR2 →	+4.029	+0.004	.007	<.001	3	1
PANCREAS	ADAMTS15 →	+4.029	+0.004	.007	<.001	3	1
PANCREAS	FCGBP →	+4.614	+0.005	.004	<.001	3	1
PANCREAS	ATRX →	+4.029	+0.004	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

ADGRB3 by OR1E1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →