OR1E1

Across TCGA pan-cancer cohorts, OR1E1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of OR1E1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where OR1E1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR1E1 is over-expressed in tumor, although a few such as BLCA and BRCA show the opposite, repressed pattern.

BLCA, BRCA, and COAD are the cancer types where OR1E1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR1E1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	IV	−0.104	.012	8	view →
BRCA	All	III,IV	−0.154	<.001	6	view →
COAD	All	II,III,IV	−0.025	.020	4	view →
KIRC	All	III,IV	−0.025	.003	4	view →
KICH	All	All	−0.076	.002	3	view →
KIRP	All	All	−0.022	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

OR1E1–BLCA

Open the BLCA breakdown →