Across TCGA cell cohorts, OR1C1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR1C1-associated genes across cancer lineages are SSX3, BPIFA1, and KRTAP10-10. Each is linked with OR1C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1C1-to-partner and partner-to-OR1C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1C1→partner) and Y-score (partner→OR1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SSX3 →	+0.332	+2.621	.003	.008	3	2
LARGE_INTESTINE	BPIFA1 →	+0.152	+2.688	<.001	.008	3	2
OESOPHAGUS	KRTAP10-10 →	+0.020	+4.906	<.001	.006	3	1
STOMACH	OR3A1 →	+0.070	+4.285	<.001	.007	3	1
STOMACH	FTMT →	+0.050	+4.285	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR1L6 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

OR1C1 survival (RNA) · tumor vs normal (RNA) · all OR1C1 data types