OR14C36

Across TCGA patient cohorts, OR14C36 mutation is significantly associated with the RNA expression of many other genes, with 2,501 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR14C36-associated genes across cancer lineages are RNU4-4P, SF3B2, and CHAF1B. Each is linked with OR14C36 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR14C36-to-partner and partner-to-OR14C36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-4P grouped by OR14C36-low versus OR14C36-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14C36→partner) and Y-score (partner→OR14C36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU4-4P →	+0.328	+3.301	.002	.008	3	3
LUAD	SF3B2 →	+0.430	+2.736	<.001	.003	3	3
UCEC	CHAF1B →	+0.687	+2.874	<.001	<.001	3	3
SKCM	ANO10 →	+0.501	+2.366	<.001	<.001	3	3
SKCM	CLPB →	+0.498	+3.504	.001	<.001	3	3
SKCM	ZFPL1 →	+0.404	+2.813	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,501 associations by consensus.

RNU4-4P by OR14C36 expression — HNSC

Explore this box plot interactively →