OR14C36

Across TCGA cell cohorts, OR14C36 mutation is significantly associated with the RNA expression of many other genes, with 552 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR14C36-associated genes across cancer lineages are ZFAND4, IFNA8, and C20orf173. Each is linked with OR14C36 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14C36-to-partner and partner-to-OR14C36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZFAND4 grouped by OR14C36-low versus OR14C36-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14C36→partner) and Y-score (partner→OR14C36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZFAND4 →	+0.940	+3.212	<.001	.006	3	2
SOFT_TISSUE	IFNA8 →	+0.052	+4.930	<.001	.008	3	1
SOFT_TISSUE	C20orf173 →	+0.025	+4.930	<.001	.008	3	1
SOFT_TISSUE	A3GALT2 →	+0.052	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR2W1 →	+0.023	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRTAP2-4 →	+0.147	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 552 associations by consensus.

ZFAND4 by OR14C36 expression — LARGE_INTESTINE

Explore this box plot interactively →