OR14A16

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR14A16 mutation is significantly associated with the RNA expression of many other genes, with 1,818 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR14A16-associated genes across cancer lineages are SNORA10B, NME1-NME2, and SYNJ2BP-COX16. Each is linked with OR14A16 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR14A16-to-partner and partner-to-OR14A16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14A16→partner) and Y-score (partner→OR14A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCSNORA10B →+0.640+5.878<.001.00233
LUADNME1-NME2 →+0.670+3.240<.001.00933
UCECSYNJ2BP-COX16 →+0.326+3.532<.001.00233
UCECMRPS11 →+0.392+2.765.003.00233
SKCMNR2C2AP →+0.364+2.728<.001.00333
SKCMSLC9A1 →+0.414+2.550.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,818 associations by consensus.

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