Across TCGA cell cohorts, OR14A16 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR14A16-associated genes across cancer lineages are SLC36A3, TP53TG3E, and KLRB1. Each is linked with OR14A16 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14A16-to-partner and partner-to-OR14A16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14A16→partner) and Y-score (partner→OR14A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC36A3 →	+0.015	+3.684	<.001	.006	3	2
BLOOD_Lymphoma	TP53TG3E →	+0.028	+5.209	<.001	.005	3	1
SKIN	KLRB1 →	+0.049	+3.584	.003	.003	3	1
SKIN	C14orf178 →	+0.105	+3.013	.002	.005	3	1
LUNG_SCLC	IFNL3 →	+0.044	+3.817	<.001	.004	3	1
LUNG_SCLC	PRR9 →	+0.073	+3.523	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

OR14A16 survival (RNA) · tumor vs normal (RNA) · all OR14A16 data types