OR13C4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR13C4 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR13C4-associated genes across cancer lineages are APOL5, UNCX, and TEX55. Each is linked with OR13C4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13C4-to-partner and partner-to-OR13C4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOL5 grouped by OR13C4-low versus OR13C4-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13C4→partner) and Y-score (partner→OR13C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTAPOL5 →+0.011+4.217.002.00531
URINARY_TRACTUNCX →+0.010+4.087<.001.00931
CNSTEX55 →+0.037+4.321<.001.00931
CNSOR11H6 →+0.016+4.321.001.00931
CNSHELT →+0.027+4.321<.001.00931
SKINGZMH →+0.016+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

APOL5 by OR13C4 expression — URINARY_TRACT

Box plot of APOL5 in OR13C4-low vs OR13C4-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration