OR12D3

Across TCGA patient cohorts, OR12D3 mutation is significantly associated with the RNA expression of many other genes, with 882 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR12D3-associated genes across cancer lineages are DPM2, XRCC6, and LINC02438. Each is linked with OR12D3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR12D3-to-partner and partner-to-OR12D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPM2 grouped by OR12D3-low versus OR12D3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR12D3→partner) and Y-score (partner→OR12D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DPM2 →	+0.403	+2.421	.004	.002	3	3
UCEC	XRCC6 →	+0.494	+3.354	.007	.005	3	3
UCEC	LINC02438 →	+0.590	+3.700	.003	.001	3	3
UCEC	FRG1HP →	+0.519	+3.732	.007	<.001	3	2
SKCM	RN7SL703P →	+0.062	+2.961	<.001	.002	3	2
UCEC	TOMM22 →	+0.660	+3.721	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 882 associations by consensus.

DPM2 by OR12D3 expression — SKCM

Explore this box plot interactively →