OR12D3

Across TCGA cell cohorts, OR12D3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR12D3-associated genes across cancer lineages are RFPL3, OLIG3, and ELOA3DP. Each is linked with OR12D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR12D3-to-partner and partner-to-OR12D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFPL3 grouped by OR12D3-low versus OR12D3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR12D3→partner) and Y-score (partner→OR12D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RFPL3 →	+0.061	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OLIG3 →	+0.024	+4.095	.008	.009	3	1
LARGE_INTESTINE	ELOA3DP →	+0.023	+4.273	.003	.006	3	1
LUNG_NSCLC_LUAD	FSHR →	+0.070	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	RNASE8 →	+0.045	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	SPATA31A3 →	+0.219	+4.189	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RFPL3 by OR12D3 expression — LARGE_INTESTINE

Explore this box plot interactively →