OR12D2

Across TCGA cell cohorts, OR12D2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR12D2-associated genes across cancer lineages are SERPINA7, ADORA3, and COL6A5. Each is linked with OR12D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR12D2-to-partner and partner-to-OR12D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by OR12D2-low versus OR12D2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR12D2→partner) and Y-score (partner→OR12D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SERPINA7 →	+0.043	+4.817	<.001	.001	3	1
LUNG_SCLC	ADORA3 →	+0.277	+4.523	<.001	.003	3	1
SKIN	COL6A5 →	+0.183	+3.823	.004	.006	3	1
SKIN	XKR4 →	+0.197	+3.684	.001	.009	3	1
BLOOD_Leukemia	SPO11 →	+0.022	+5.969	<.001	.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.026	+4.688	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

SERPINA7 by OR12D2 expression — LUNG_SCLC

Explore this box plot interactively →