OR12D2

Across TCGA pan-cancer cohorts, OR12D2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR12D2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR12D2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR12D2 is over-expressed in tumor.

KIRC, CHOL, and LUAD are the cancer types where OR12D2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR12D2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.023	.029	3	view →
CHOL	All	All	+0.603	.020	1	view →
LUAD	Male	All	+0.026	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

OR12D2–KIRC

Open the KIRC breakdown →