OR12D1

Across TCGA pan-cancer cohorts, OR12D1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated OR12D1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher OR12D1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR12D1 expression acts as an unfavorable survival marker, although some lineages such as CHOL show a favorable association.

MESO, COAD, and LIHC are the cancer types where OR12D1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.077	0.580	<.001	126	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	99	view →
LIHC	DFS	Tertile	All	0.277	0.459	<.001	57	view →
BLCA	OS	Tertile	III,IV	0.052	0.582	<.001	45	view →
UCEC	OS	Tertile	All	0.806	0.933	<.001	42	view →
STAD	DFS	Tertile	All	0.538	0.671	.012	36	view →
ESCA	OS	Tertile	All	0.207	0.909	.002	36	view →
KIRP	DFS	Tertile	II,III,IV	0.463	0.823	.004	36	view →
LGG	DFS	Tertile	All	0.565	0.759	<.001	33	view →
KIRC	DFS	Tertile	All	0.425	0.669	.003	18	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
THCA	OS	Tertile	II,III,IV	0.323	0.914	.019	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

OR12D1–MESO (OS)

Open the MESO breakdown →