OR11H7

Across TCGA pan-cancer cohorts, OR11H7 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of OR11H7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR11H7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR11H7 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, LUSC, and KIRC are the cancer types where OR11H7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR11H7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.920	<.001	11	view →
LUSC	Female	II,III,IV	+0.815	<.001	8	view →
KIRC	Male	All	+0.136	<.001	8	view →
BRCA	All	III,IV	−0.334	<.001	6	view →
STAD	All	II,III,IV	+0.134	.011	4	view →
BLCA	All	All	+0.430	.025	2	view →
LUAD	All	All	+0.168	.015	2	view →
CHOL	All	All	+0.135	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

OR11H7–HNSC

Open the HNSC breakdown →