OR11H6

Across TCGA patient cohorts, OR11H6 mutation is significantly associated with the RNA expression of many other genes, with 677 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR11H6-associated genes across cancer lineages are PPP1R36, BRI3, and IRGQ. Each is linked with OR11H6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR11H6-to-partner and partner-to-OR11H6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R36 grouped by OR11H6-low versus OR11H6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11H6→partner) and Y-score (partner→OR11H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R36 →	-0.659	-2.906	.001	.002	3	3
UCEC	BRI3 →	+0.385	+2.741	.008	.003	3	2
UCEC	IRGQ →	+0.503	+2.265	.001	.006	3	2
UCEC	PHPT1 →	+0.468	+3.353	.006	.005	3	2
LUSC	MCOLN1 →	+0.524	+3.471	<.001	.002	3	2
UCEC	MIR7702 →	+0.214	+4.153	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 677 associations by consensus.

PPP1R36 by OR11H6 expression — UCEC

Explore this box plot interactively →