OR11H6

Across TCGA pan-cancer cohorts, OR11H6 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR11H6’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR11H6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR11H6 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

LUSC, HNSC, and BRCA are the cancer types where OR11H6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR11H6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.053	<.001	5	view →
HNSC	All	III,IV	+0.024	.007	5	view →
BRCA	All	All	−0.019	.004	3	view →
BLCA	All	All	+0.058	.021	2	view →
THCA	Female	All	−0.010	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR11H6–LUSC

Open the LUSC breakdown →