OR11H6

Across TCGA patient cohorts, OR11H6 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR11H6-associated genes across cancer lineages are CDK1, Rictor_pT1135, and IRS1. Each is linked with OR11H6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11H6-to-partner and partner-to-OR11H6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDK1 grouped by OR11H6-low versus OR11H6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11H6→partner) and Y-score (partner→OR11H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDK1 →	+0.152	+2.000	.025	.032	3	2
LUSC	Rictor_pT1135 →	+0.174	+2.816	.010	.036	3	1
SKCM	IRS1 →	+0.158	+2.186	.006	.032	3	1
SKCM	PKC-a →	-0.349	-1.678	.024	.022	3	1
SKCM	Src_pY527 →	+0.342	+3.000	.036	.034	3	1
SKCM	Src →	+0.193	+1.753	.028	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

CDK1 by OR11H6 expression — UCEC

Explore this box plot interactively →