OR11H12

Across TCGA patient cohorts, OR11H12 mutation is significantly associated with the RNA expression of many other genes, with 512 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR11H12-associated genes across cancer lineages are RNU6-229P, DUX4L19, and MIR5091. Each is linked with OR11H12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11H12-to-partner and partner-to-OR11H12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-229P grouped by OR11H12-low versus OR11H12-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11H12→partner) and Y-score (partner→OR11H12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-229P →	+0.408	+5.912	<.001	.002	3	2
HNSC	DUX4L19 →	+0.065	+5.303	<.001	.006	3	2
UCEC	MIR5091 →	+0.961	+4.093	<.001	.001	3	2
UCEC	MIR188 →	+0.240	+4.260	.007	.007	3	2
UCEC	PSAT1P4 →	+0.212	+4.148	.004	.001	3	2
UCEC	SNORA84 →	+0.890	+3.580	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 512 associations by consensus.

RNU6-229P by OR11H12 expression — HNSC

Explore this box plot interactively →