Across TCGA patient cohorts, OR11A1 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR11A1-associated genes across cancer lineages are Notch1, C-Raf, and GAPDH. Each is linked with OR11A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11A1-to-partner and partner-to-OR11A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11A1→partner) and Y-score (partner→OR11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.174	+2.469	.002	.010	3	2
UCEC	C-Raf →	+0.210	+2.459	<.001	.019	3	2
UCEC	GAPDH →	+0.481	+1.807	.030	.027	3	1
UCEC	ACC1 →	+0.403	+3.183	.007	.009	3	1
UCEC	Heregulin →	-0.114	-3.156	.024	.018	3	1
UCEC	INPP4B →	-0.292	-2.308	.029	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

OR11A1 survival (RNA) · tumor vs normal (RNA) · all OR11A1 data types