Across TCGA cell cohorts, OR11A1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR11A1-associated genes across cancer lineages are KRT25, RPTN, and OR51F2. Each is linked with OR11A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11A1-to-partner and partner-to-OR11A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11A1→partner) and Y-score (partner→OR11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	KRT25 →	+0.035	+4.643	<.001	.004	3	1
LUNG_SCLC	RPTN →	+0.006	+4.269	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR51F2 →	+0.016	+4.662	<.001	.005	3	1
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

OR11A1 survival (RNA) · tumor vs normal (RNA) · all OR11A1 data types