OR10W1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10W1 mutation is significantly associated with the RNA expression of many other genes, with 2,432 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10W1-associated genes across cancer lineages are DUSP3, RNA5SP415, and UTP14C. Each is linked with OR10W1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10W1-to-partner and partner-to-OR10W1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUSP3 grouped by OR10W1-low versus OR10W1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10W1→partner) and Y-score (partner→OR10W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADDUSP3 →+0.438+3.356.002.00433
LUADRNA5SP415 →+0.093+4.014<.001.00733
LUADUTP14C →+0.455+2.632.007.00533
UCECRAB5C →+0.488+3.732.002<.00133
UCECTACO1 →+0.374+3.732.003<.00133
UCECWRAP53 →+0.407+2.269.006.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,432 associations by consensus.

DUSP3 by OR10W1 expression — LUAD

Box plot of DUSP3 in OR10W1-low vs OR10W1-high samples in LUAD.

Explore this box plot interactively →

Exploration