OR10V1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10V1 mutation is significantly associated with the RNA expression of many other genes, with 598 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10V1-associated genes across cancer lineages are RNA5SP461, GOLGA2P2Y, and RN7SL709P. Each is linked with OR10V1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10V1-to-partner and partner-to-OR10V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP461 grouped by OR10V1-low versus OR10V1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10V1→partner) and Y-score (partner→OR10V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP461 →+0.263+4.253<.001.00433
COADGOLGA2P2Y →+0.053+5.003<.001.00432
SKCMRN7SL709P →+0.069+3.224<.001.00732
BLCAZNF736P8Y →+0.059+7.640<.001.00932
SKCMRN7SL330P →+0.110+3.005.009.00332
HNSCSNORA36A →+0.389+5.241<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 598 associations by consensus.

RNA5SP461 by OR10V1 expression — UCEC

Box plot of RNA5SP461 in OR10V1-low vs OR10V1-high samples in UCEC.

Explore this box plot interactively →

Exploration