OR10V1

Across TCGA pan-cancer cohorts, OR10V1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR10V1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR10V1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR10V1 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.

BRCA, LUSC, and STAD are the cancer types where OR10V1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR10V1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.025	<.001	4	view →
LUSC	All	All	−0.021	.010	3	view →
STAD	Male	II,III,IV	−0.054	.027	2	view →
PRAD	All	All	−0.013	.028	2	view →
HNSC	All	IV	+0.036	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR10V1–BRCA

Open the BRCA breakdown →