OR10V1

Across TCGA patient cohorts, OR10V1 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10V1-associated genes across cancer lineages are S6_pS240_S244, EGFR_pY1068, and GATA6. Each is linked with OR10V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10V1-to-partner and partner-to-OR10V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S6_pS240_S244 grouped by OR10V1-low versus OR10V1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10V1→partner) and Y-score (partner→OR10V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	S6_pS240_S244 →	+0.384	+2.700	.036	.006	3	2
UCEC	EGFR_pY1068 →	-0.303	-2.700	.007	.006	3	1
UCEC	GATA6 →	-0.148	-2.577	.040	.011	3	1
UCEC	JNK_pT183_Y185 →	-0.156	-1.986	.040	.032	3	1
UCEC	N-Cadherin →	+0.211	+2.179	.027	.034	3	1
UCEC	NDRG1_pT346 →	-0.485	-2.000	.028	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

S6_pS240_S244 by OR10V1 expression — UCEC

Explore this box plot interactively →