OR10V1

Across TCGA cell cohorts, OR10V1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR10V1-associated genes across cancer lineages are MAGEC3, COX6A2, and IFNA14. Each is linked with OR10V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10V1-to-partner and partner-to-OR10V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEC3 grouped by OR10V1-low versus OR10V1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10V1→partner) and Y-score (partner→OR10V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MAGEC3 →	+0.272	+3.855	<.001	.007	3	2
URINARY_TRACT	COX6A2 →	+0.123	+5.087	<.001	.004	3	1
URINARY_TRACT	IFNA14 →	+0.026	+5.087	<.001	.004	3	1
LARGE_INTESTINE	GJD2 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1
BLOOD_Leukemia	GML →	+0.058	+4.567	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MAGEC3 by OR10V1 expression — BLOOD_Leukemia

Explore this box plot interactively →