Across TCGA pan-cancer cohorts, OR10S1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR10S1 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR10S1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR10S1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and SCLC show a favorable association.

COAD, GBM, and LUSC are the cancer types where OR10S1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	III,IV	0.056	0.783	<.001	25	view →
GBM	OS	Median	All	0.071	0.415	<.001	9	view →
LUSC	OS	Median	All	0.785	0.387	.016	5	view →
SCLC	DFS	Median	III,IV	1.000	0.211	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR10S1 tumor-vs-normal RNA expression · all OR10S1 data types