Across TCGA patient cohorts, OR10S1 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR10S1-associated genes across cancer lineages are 4E-BP1, Smad4, and 4E-BP1_pT70. Each is linked with OR10S1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR10S1-to-partner and partner-to-OR10S1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10S1→partner) and Y-score (partner→OR10S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.418	+3.029	.001	.018	3	3
SKCM	Smad4 →	+0.113	+1.678	.008	.022	3	3
LUAD	4E-BP1_pT70 →	+0.313	+2.824	.004	.036	3	2
LUSC	4E-BP1_pS65 →	+0.399	+3.335	<.001	.005	3	2
UCEC	MEK1 →	+0.483	+2.459	.006	.020	3	2
UCEC	PCNA →	+0.341	+3.584	.001	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

OR10S1 survival (RNA) · tumor vs normal (RNA) · all OR10S1 data types