OR10R2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10R2 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10R2-associated genes across cancer lineages are p62 Lck ligand, PDK1, and eEF2. Each is linked with OR10R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10R2-to-partner and partner-to-OR10R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10R2→partner) and Y-score (partner→OR10R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp62 Lck ligand →+0.513+2.321.001.03532
SKCMPDK1 →-0.099-1.756.026.02732
UCECeEF2 →+0.490+2.321.006.03531
UCECeIF4G →+0.334+2.321.032.03531
UCECMIG-6 →+0.111+2.335.026.02031
UCECN-Cadherin →+0.250+2.321.019.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration