OR10K2

Across TCGA patient cohorts, OR10K2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,510 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR10K2-associated GO terms across cancer lineages are tRNA metabolic process, tRNA processing, and Protein localization to mitochondrion. Each is linked with OR10K2 in more than 9 cancer types. Because this analysis shows association rather than direction, both OR10K2-to-partner and partner-to-OR10K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by OR10K2-low versus OR10K2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10K2→partner) and Y-score (partner→OR10K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA metabolic process →	+0.095	+0.141	<.001	<.001	3	10
STAD	tRNA processing →	+0.092	+0.136	<.001	<.001	3	10
STAD	Protein localization to mitochondrion →	+0.093	+0.143	<.001	<.001	3	9
STAD	Methylation →	+0.088	+0.167	<.001	<.001	3	9
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.103	+0.139	<.001	<.001	3	9
STAD	Nucleoside phosphate biosynthetic process →	+0.088	+0.132	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,510 associations by consensus.

tRNA metabolic process by OR10K2 expression — STAD

Explore this box plot interactively →