OR10K2

Across TCGA cell cohorts, OR10K2 RNA expression is significantly associated with the mutation status of many other genes, with 496 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR10K2-associated genes across cancer lineages are SLC5A1, VPS18, and MYH3. Each is linked with OR10K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10K2-to-partner and partner-to-OR10K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A1 grouped by OR10K2-low versus OR10K2-high in BREAST.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10K2→partner) and Y-score (partner→OR10K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SLC5A1 →	+5.781	+0.063	.001	<.001	3	2
BREAST	VPS18 →	+4.781	+0.047	.003	<.001	3	2
BREAST	MYH3 →	+4.781	+0.047	.003	<.001	3	2
BREAST	ATG2A →	+4.781	+0.047	.003	<.001	3	2
BREAST	UNK →	+4.196	+0.038	.006	<.001	3	2
BLOOD_Leukemia	KRBA1 →	+5.121	+0.053	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 496 associations by consensus.

SLC5A1 by OR10K2 expression — BREAST

Explore this box plot interactively →