OR10H4

Across TCGA patient cohorts, OR10H4 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10H4-associated genes across cancer lineages are SLC1A5, eEF2, and EGFR_pY1068. Each is linked with OR10H4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10H4-to-partner and partner-to-OR10H4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC1A5 grouped by OR10H4-low versus OR10H4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H4→partner) and Y-score (partner→OR10H4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC1A5 →	-0.445	-2.314	.037	.035	3	2
UCEC	eEF2 →	+0.403	+2.321	.024	.035	3	1
UCEC	EGFR_pY1068 →	-0.353	-3.459	.005	.005	3	1
UCEC	A-Raf_pS299 →	-0.190	-3.000	.001	.036	3	1
UCEC	GATA6 →	-0.191	-3.452	.013	.005	3	1
UCEC	JNK_pT183_Y185 →	-0.203	-2.308	.016	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

SLC1A5 by OR10H4 expression — UCEC

Explore this box plot interactively →