OR10H4

Across TCGA pan-cancer cohorts, OR10H4 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated OR10H4 data layer compared with 3 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OR10H4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR10H4 expression acts as an unfavorable survival marker, although some lineages such as MESO and SKCM show a favorable association.

ACC, COAD, and SCLC are the cancer types where OR10H4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	117	view →
COAD	OS	Tertile	All	0.159	0.799	.002	54	view →
SCLC	OS	Tertile	All	0.055	0.708	<.001	36	view →
SARC	DFS	Tertile	All	0.161	0.616	<.001	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
MESO	OS	Tertile	All	0.941	0.254	.018	12	view →
SKCM	DFS	Tertile	All	0.567	0.195	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

OR10H4–ACC (OS)

Open the ACC breakdown →