OR10H2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10H2 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10H2-associated genes across cancer lineages are NKT, lymphatic Endothelial cells, and iDC. Each is linked with OR10H2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10H2-to-partner and partner-to-OR10H2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKT grouped by OR10H2-low versus OR10H2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10H2→partner) and Y-score (partner→OR10H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNKT →-0.105-2.676.017.00633
UCEClymphatic Endothelial cells →-0.020-3.544.036.00232
SKCMiDC →-0.115-1.356.041.03731
UCECMEP →+0.028+2.202.014.03431
UCECmv Endothelial cells →-0.020-2.947.038.03631
UCECBasophils →+0.195+2.321.005.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

NKT by OR10H2 expression — UCEC

Box plot of NKT in OR10H2-low vs OR10H2-high samples in UCEC.

Explore this box plot interactively →

Exploration