OR10G3

Across TCGA patient cohorts, OR10G3 mutation is significantly associated with the RNA expression of many other genes, with 469 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10G3-associated genes across cancer lineages are RNY4P14, GAPDHP22, and CORO1C. Each is linked with OR10G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G3-to-partner and partner-to-OR10G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P14 grouped by OR10G3-low versus OR10G3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G3→partner) and Y-score (partner→OR10G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNY4P14 →	+0.563	+5.330	<.001	.001	3	2
UCEC	GAPDHP22 →	+0.449	+2.671	<.001	.006	3	2
UCEC	CORO1C →	+0.598	+2.617	.001	.005	3	2
SKCM	SDHB →	+0.752	+3.353	<.001	.005	3	2
UCEC	TM4SF19-TCTEX1D2 →	-0.090	-3.767	.005	<.001	3	1
UCEC	TAF9 →	+0.635	+2.700	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 469 associations by consensus.

RNY4P14 by OR10G3 expression — LUAD

Explore this box plot interactively →