Across TCGA pan-cancer cohorts, OR10AA1P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR10AA1P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR10AA1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR10AA1P is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.
KIRC, THCA, and LUAD are the cancer types where OR10AA1P tumor–normal differential expression is most reproducible.