OR10A2

Across TCGA cell cohorts, OR10A2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10A2-associated genes across cancer lineages are TAAR6, KCNK16, and OR10W1. Each is linked with OR10A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A2-to-partner and partner-to-OR10A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR6 grouped by OR10A2-low versus OR10A2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A2→partner) and Y-score (partner→OR10A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	TAAR6 →	+0.043	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KCNK16 →	+0.030	+4.807	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.016	+3.977	<.001	.001	3	1
LARGE_INTESTINE	OR10Q1 →	+0.093	+4.242	.003	.001	3	1
LARGE_INTESTINE	MRGPRE →	+0.062	+3.459	.003	.009	3	1
LARGE_INTESTINE	NAT8 →	+0.998	+3.443	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TAAR6 by OR10A2 expression — BLOOD_Myeloma

Explore this box plot interactively →