OR10A2

Across TCGA pan-cancer cohorts, OR10A2 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated OR10A2 data layer compared with 4 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR10A2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR10A2 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

DLBC, TGCT, and ACC are the cancer types where OR10A2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	IV	0.125	0.744	<.001	78	view →
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	72	view →
ACC	DFS	Tertile	II,III,IV	0.136	0.753	<.001	63	view →
BLCA	DFS	Tertile	All	0.508	0.649	.011	51	view →
KIRC	OS	Quartile	All	0.505	0.653	.007	39	view →
CESC	OS	Tertile	IV	0.091	0.593	<.001	36	view →
KICH	OS	Tertile	All	0.267	0.893	<.001	33	view →
LAML	DFS	Tertile	All	0.214	0.458	.009	28	view →
LIHC	OS	Tertile	II,III,IV	0.125	0.622	.001	27	view →
ESCA	DFS	Tertile	II,III,IV	0.488	0.289	.024	23	view →
UCS	DFS	Tertile	IV	0.318	0.745	.042	18	view →
GBM	OS	Tertile	All	0.195	0.422	.003	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

OR10A2–DLBC (DFS)

Open the DLBC breakdown →