OPRPN

Across TCGA patient cohorts, OPRPN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,493 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OPRPN-associated GO terms across cancer lineages are Protein stabilization, Cytoplasmic translation, and Response to alcohol. Each is linked with OPRPN in more than 7 cancer types. Because this analysis shows association rather than direction, both OPRPN-to-partner and partner-to-OPRPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by OPRPN-low versus OPRPN-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OPRPN→partner) and Y-score (partner→OPRPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein stabilization →	+0.074	+0.111	<.001	<.001	3	8
STAD	Cytoplasmic translation →	+0.099	+0.101	<.001	<.001	3	8
STAD	Response to alcohol →	+0.051	+0.088	<.001	<.001	3	8
STAD	Mitochondrial membrane organization →	+0.077	+0.091	<.001	<.001	3	7
STAD	Electron transport chain →	+0.109	+0.180	<.001	<.001	3	7
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.083	+0.102	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,493 associations by consensus.

Protein stabilization by OPRPN expression — STAD

Explore this box plot interactively →