OPRD1

Across TCGA pan-cancer cohorts, OPRD1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated OPRD1 data layer compared with 21 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OPRD1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated OPRD1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC and GBM are the cancer types where OPRD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.238	.024	12	view →
GBM	DFS	Quartile	All	0.531	0.249	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

OPRD1–UCEC (DFS)

Open the UCEC breakdown →