OPN4

Across TCGA patient cohorts, OPN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,858 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OPN4-associated proteins across cancer lineages are PRRC2C, SEPTIN4, and BZW2. Each is linked with OPN4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OPN4-to-partner and partner-to-OPN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPN4 versus PRRC2C in BRCA, with a Pearson correlation of -0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN4→partner) and Y-score (partner→OPN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRRC2C →	-0.159	-0.125	.002	.003	3	3
GBM	SEPTIN4 →	+0.668	+0.306	<.001	<.001	3	3
GBM	BZW2 →	-0.377	-0.332	<.001	<.001	3	3
CCRCC	CNRIP1 →	+0.533	+0.377	<.001	.004	3	3
BRCA	AHNAK_S4908 →	+0.558	+0.166	<.001	.003	3	3
CCRCC	EPRS1 →	-0.213	-0.430	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,858 associations by consensus.

OPN4 vs PRRC2C — BRCA

Explore this scatter interactively →