Across TCGA patient cohorts, OPN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,030 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OPN4-associated GO terms across cancer lineages are Detection of temperature stimulus involved in thermoception, Positive regulation of vasculature development, and Regulation of endothelial cell migration. Each is linked with OPN4 in more than 23 cancer types. Because this analysis shows association rather than direction, both OPN4-to-partner and partner-to-OPN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN4→partner) and Y-score (partner→OPN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	Detection of temperature stimulus involved in thermoception →	-0.131	-0.299	<.001	<.001	2	24
STAD	Positive regulation of vasculature development →	+0.050	+0.099	<.001	<.001	3	20
STAD	Regulation of endothelial cell migration →	+0.053	+0.108	<.001	<.001	3	19
TGCT	Endocardial cushion morphogenesis →	+0.056	+0.081	<.001	.001	3	19
STAD	Glomerulus development →	+0.058	+0.112	<.001	<.001	3	19
TGCT	Mesenchyme morphogenesis →	+0.064	+0.071	<.001	.003	2	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,030 associations by consensus.

Exploration

OPN4 survival (RNA) · tumor vs normal (RNA) · all OPN4 data types