OPN4

Across TCGA patient cohorts, OPN4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,113 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OPN4-associated genes across cancer lineages are PRODH, MFNG, and MCAT. Each is linked with OPN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OPN4-to-partner and partner-to-OPN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPN4 versus PRODH in GBM, with a Pearson correlation of -0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN4→partner) and Y-score (partner→OPN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	-1.860	-1.039	.008	.007	3	1
GBM	MFNG →	+1.089	+1.110	.003	.002	3	1
GBM	MCAT →	-0.639	-1.493	.005	<.001	3	1
GBM	STK4 →	+0.447	+1.110	.001	.002	3	1
GBM	SLC17A9 →	+0.876	+1.110	.003	.002	3	1
GBM	TLDC2 →	+0.711	+1.110	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,113 associations by consensus.

OPN4 vs PRODH — GBM

Explore this scatter interactively →