OPN1SW

Across TCGA patient cohorts, OPN1SW mutation is significantly associated with the RNA expression of many other genes, with 533 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OPN1SW-associated genes across cancer lineages are FGF12-AS1, RN7SL634P, and SUMO2P7. Each is linked with OPN1SW in more than 1 cancer types. Because this analysis shows association rather than direction, both OPN1SW-to-partner and partner-to-OPN1SW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF12-AS1 grouped by OPN1SW-low versus OPN1SW-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1SW→partner) and Y-score (partner→OPN1SW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FGF12-AS1 →	+0.077	+3.578	.004	.007	3	2
COAD	RN7SL634P →	+0.197	+3.730	.006	.004	3	2
UCEC	SUMO2P7 →	+0.231	+1.932	.003	<.001	3	2
SKCM	HSBP1P1 →	+0.361	+3.915	<.001	.002	3	2
SKCM	OR10K2 →	+0.041	+4.328	<.001	.007	3	1
SKCM	SERPINA13P →	+0.018	+4.199	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 533 associations by consensus.

FGF12-AS1 by OPN1SW expression — SKCM

Explore this box plot interactively →